Liquid‐Phase Exfoliation and Functionalization of MoS2 Nanosheets for Effective Antibacterial Application

A lysozyme (Lys)‐assisted liquid‐phase exfoliation technique was designed to synthesize MoS2 nanosheets (MoS2‐Lys NSs). As a novel nanozyme antibacterial agent with high peroxidase‐like catalyst activity, MoS2‐Lys NSs showed good antibacterial efficacy against both Gram‐negative ampicillin‐resistant...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2020-08, Vol.21 (16), p.2373-2380
Hauptverfasser: Ma, Dongqing, Xie, Changjian, Wang, Tao, Mei, Linqiang, Zhang, Xiao, Guo, Zhao, Yin, Wenyan
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Sprache:eng
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Zusammenfassung:A lysozyme (Lys)‐assisted liquid‐phase exfoliation technique was designed to synthesize MoS2 nanosheets (MoS2‐Lys NSs). As a novel nanozyme antibacterial agent with high peroxidase‐like catalyst activity, MoS2‐Lys NSs showed good antibacterial efficacy against both Gram‐negative ampicillin‐resistant Escherichia coli (Ampr E. coli) and Gram‐positive Bacillus subtilis. A possible antibacterial mechanism is also proposed. This work provides an effective antibacterial strategy based on the MoS2‐Lys NSs antibacterial agent. Plusses and minuses: A lysozyme (Lys)‐assisted liquid‐phase exfoliation technique was designed to synthesize MoS2 nanosheets (MoS2‐Lys NSs). The MoS2‐Lys NSs as effective nanozyme antibacterial agent with high peroxidase‐like catalytic activity showed efficient antibacterial activity against both Gram‐negative Ampr E. coli and Gram‐positive B. subtilis.
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.202000195