Clinical impact of controlling nutritional status score on the prognosis of patients with diffuse large B‐cell lymphoma

Clinical impact of controlling nutritional status score on the prognosis of patients with diffuse large B‐cell lymphoma

The controlling nutritional status (CONUT) score is a nutritional index calculated from serum albumin and total cholesterol levels and lymphocyte counts. Its role in predicting clinical outcomes of diffuse large B‐cell lymphoma (DLBCL) has not been evaluated. In this retrospective study, data from 4...

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Veröffentlicht in:Hematological oncology 2020-08, Vol.38 (3), p.309-317
Hauptverfasser: Nagata, Akihito, Kanemasa, Yusuke, Sasaki, Yuki, Nakamura, Shohei, Okuya, Toshihiro, Funasaka, Chikako, Kageyama, Akihiko, Shimoyama, Tatsu, Omuro, Yasushi
Format: Artikel
Sprache:eng
Schlagworte:
B-cell lymphoma
Chemotherapy
Cholesterol
CONUT score
diffuse large B‐cell lymphoma
Lymphocytes
Lymphoma
Medical prognosis
Nutrition assessment
Nutritional status
prognostic score
RDI
Risk
Serum albumin
Survival
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Zusammenfassung:The controlling nutritional status (CONUT) score is a nutritional index calculated from serum albumin and total cholesterol levels and lymphocyte counts. Its role in predicting clinical outcomes of diffuse large B‐cell lymphoma (DLBCL) has not been evaluated. In this retrospective study, data from 476 patients with DLBCL were analyzed. The cutoff value of the CONUT score was set as 4. CONUT score significantly stratified the overall survival (OS) and the progression‐free‐survival (PFS) (5‐year OS, 49.0% vs 83.2%, P 
ISSN:0278-0232
1099-1069
DOI:10.1002/hon.2732