Procedural, pregnancy, and short‐term outcomes after fetal aortic valvuloplasty
Objectives We aimed to evaluate the effect of technical aspects of fetal aortic valvuloplasty (FAV) on procedural risks and pregnancy outcomes. Background FAV is performed in cases of severe mid‐gestation aortic stenosis with the goal of preventing hypoplastic left heart syndrome (HLHS). Methods The...
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Veröffentlicht in: | Catheterization and cardiovascular interventions 2020-09, Vol.96 (3), p.626-632 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objectives
We aimed to evaluate the effect of technical aspects of fetal aortic valvuloplasty (FAV) on procedural risks and pregnancy outcomes.
Background
FAV is performed in cases of severe mid‐gestation aortic stenosis with the goal of preventing hypoplastic left heart syndrome (HLHS).
Methods
The International Fetal Cardiac Intervention Registry was queried for fetuses who underwent FAV from 2002 to 2018, excluding one high‐volume center.
Results
The 108 fetuses had an attempted cardiac puncture (mean gestational age [GA] 26.1 ± 3.3 weeks). 83.3% of attempted interventions were technically successful (increased forward flow/new aortic insufficiency). The interventional cannula was larger than 19 g in 70.4%. More than one cardiac puncture was performed in 25.0%. Intraprocedural complications occurred in 48.1%, including bradycardia (34.1%), pericardial (22.2%) or pleural effusion (2.7%) requiring drainage, and balloon rupture (5.6%). Death within 48 hr occurred in 16.7% of fetuses. Of the 81 patients born alive, 59 were discharged home, 34 of whom had biventricular circulation. More than one cardiac puncture was associated with higher complication rates (p |
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ISSN: | 1522-1946 1522-726X |
DOI: | 10.1002/ccd.28846 |