Intracranial hemorrhage type and same-admission mortality in patients with left ventricular assist devices

•48 % of LVAD patients die despite surgical intervention.•Hemorrhage location is a major predictor of overall outcome.•Patient counseling on the severity of intracranial hemorrhage after insertion of an LVAD device is advised. Left ventricular assist devices (LVAD) provide mechanical circulatory sup...

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Veröffentlicht in:Clinical neurology and neurosurgery 2020-06, Vol.193, p.105790-105790, Article 105790
Hauptverfasser: Mueller, Kyle B., Zhao, David, Dowlati, Ehsan, D’Antuono, Matthew, Felbaum, Daniel, Chang, Jason, Hockstein, Michael, Mai, Jeffery, Mason, Bryan, Aulisi, Edward, Armonda, Rocco
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Sprache:eng
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Zusammenfassung:•48 % of LVAD patients die despite surgical intervention.•Hemorrhage location is a major predictor of overall outcome.•Patient counseling on the severity of intracranial hemorrhage after insertion of an LVAD device is advised. Left ventricular assist devices (LVAD) provide mechanical circulatory support for patients with advanced heart failure. Intracranial hemorrhage in this population represent a significant management challenge. The objective of this study is to report our initial experience on same-admission outcomes with LVAD patients that presented with various types of intracranial hemorrhage (ICH). A retrospective review of a large volume center over a two-year period was performed. LVAD patients with ICH requiring a neurosurgical consultation were identified. Hemorrhage type, interventions, discharge disposition and cause of death were recorded. 27 LVAD patients with ICH received a neurosurgical consultation. The average INR at the time of ICH was 2.7 (1.0–8.8). Hemorrhage types seen were lobar (10/27, 37 %), SAH (5/27, 19 %), SDH (4/27, 15 %), cerebellar ICH (3/27, 11 %), multiple ICH (3/27, 11 %), and hemorrhagic conversion (2/27, 7 %). The overall mortality rate was 48.2 % (13/27), with the highest mortality being in those patients who had multiple ICH at the time of presentation (3/3, 100 %). The majority of patients with ICH (85.2 %) were non-operative. Lobar IPH was
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.105790