Effect of Physical Exercise Training in Patients With Chagas Heart Disease (from the PEACH STUDY)

•Exercise training improved functional capacity in Chagas heart disease.•Exercisers tolerate higher loads of exercise after 3- and 6 months of follow-up.•Exercise may constitute a coadjuvant strategy for patients with Chagas heart disease. Chagas heart disease (HD) is a chronic fibrosing myocarditis...

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Veröffentlicht in:	The American journal of cardiology 2020-05, Vol.125 (9), p.1413-1420
Hauptverfasser:	de Souza Nogueira Sardinha Mendes, Fernanda, Mediano, Mauro Felippe Felix, de Castro e Souza, Fernando Cesar, da Silva, Paula Simplício, Carneiro, Fernanda Martins, de Holanda, Marcelo Teixeira, Saraiva, Roberto Magalhães, Xavier, Sergio Salles, Americano do Brasil, Pedro Emmanuel Alvarenga, de Sousa, Andréa Silvestre
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaerobic threshold Biomarkers Blood tests Body composition Cardiovascular disease Cardiovascular diseases Chagas disease Congestive heart failure Coronary artery disease Echocardiography Exercise Fitness equipment Fitness training programs Heart Heart diseases Mathematical analysis Mechanical ventilation Muscles Myocarditis Oxygen consumption Patients Physical exercise Physical fitness Physical training Signs and symptoms Training Vanadium oxides Vector-borne diseases Ventilation Ventricle
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Zusammenfassung:	•Exercise training improved functional capacity in Chagas heart disease.•Exercisers tolerate higher loads of exercise after 3- and 6 months of follow-up.•Exercise may constitute a coadjuvant strategy for patients with Chagas heart disease. Chagas heart disease (HD) is a chronic fibrosing myocarditis with high mortality. The PEACH study aimed to evaluate if exercise training can improve the functional capacity of Chagas HD patients with left ventricular dysfunction and/or heart failure. The PEACH study was a single center, parallel-group, clinical trial that randomized 30 clinical stable Chagas HD patients with left ventricular ejection fraction
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2020.01.035