Bacterial vaginosis, representation of endocervical and/or metaplastic cells, and cytological abnormalities in different age groups: Association study
Background Studies have indicated that bacterial vaginosis (BV) might be a cofactor for the acquisition and persistence of high‐risk papillomavirus, enabling the development of cytological abnormalities. The presence of endocervical and metaplastic cells makes the smear more adequate for the detecti...
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Veröffentlicht in: | Diagnostic cytopathology 2020-08, Vol.48 (8), p.711-716 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background
Studies have indicated that bacterial vaginosis (BV) might be a cofactor for the acquisition and persistence of high‐risk papillomavirus, enabling the development of cytological abnormalities. The presence of endocervical and metaplastic cells makes the smear more adequate for the detection of these abnormalities once these cell types are representative of the transformation zone, a site of increased susceptibility to viral infection.
Methods
The purpose of this study was to evaluate the patterns of vaginal microbiota, the representation of endocervical and/or metaplastic cells, and the detection of cytological abnormalities in cervical smears from women 15 to 64 years old. Results from satisfactory cytological smears performed in a laboratory school from the Federal University of Goiás were analyzed. The degree of association between the categorical variables was evaluated by the χ2 test, Fisher's Exact test, and stratified analysis through the estimation of the prevalence ratio, with 95% confidence intervals and 5% statistical significance level (P |
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ISSN: | 8755-1039 1097-0339 |
DOI: | 10.1002/dc.24398 |