Associations between genetic variants of the insulin-like growth factor I (IGF-I) gene and growth traits in European sea bass (Dicentrarchus labrax, L.)

The IGF-I is a significant peptide hormone to cell growth, development, reproduction, and metabolism of teleost fish. This study was conducted to investigate the IGF-I gene polymorphism and to reveal the association between the genotypes of IGF-I gene and growth traits in 80 harvest size European se...

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Veröffentlicht in:Fish physiology and biochemistry 2020-06, Vol.46 (3), p.1131-1138
Hauptverfasser: Özcan Gökçek, Emel, Işık, Raziye
Format: Artikel
Sprache:eng
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Zusammenfassung:The IGF-I is a significant peptide hormone to cell growth, development, reproduction, and metabolism of teleost fish. This study was conducted to investigate the IGF-I gene polymorphism and to reveal the association between the genotypes of IGF-I gene and growth traits in 80 harvest size European sea bass ( Dicentrarchus labrax , L.) reared in İzmir region of Turkey. The 821 bp long exon 1 and 5’ UTR regions of IGF-I gene were amplified, and PCR products were analyzed via DNA sequencing method. Two novel single nucleotide polymorphisms (SNPs) such as g.46672A > G and g.46749C > T in the 5’ UTR region of IGF-I gene in the European sea bass were detected for the first time with this study. Associations between the genotypes of IGF-I g.46749C > T locus and body weight were found statistically significant ( p   T and g.46672A > G loci were found significantly associated with total length ( p  
ISSN:0920-1742
1573-5168
DOI:10.1007/s10695-020-00779-8