Central auditory processing in parkinsonian disorders: A systematic review

•This systematic review is the first to consider central auditory processing in parkinsonian disorders.•Parkinson’s disease is associated with distinct central auditory processing deficits.•Research on central auditory processing in atypical parkinsonian disorders is sparse.•More research is needed on the effect of dopaminergic medication and disease progression. Altered auditory processing has been increasingly recognized as a non-motor feature in parkinsonian disorders. This systematic review provides an overview of behavioral and electrophysiological literature on central auditory processing in patients with Parkinson’s disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). A systematic database search was conducted and yielded 88 studies that met the intelligibility criteria. The collected data revealed distinct impairments in a range of central auditory processes in PD, including altered deviance detection of basic auditory features, auditory brainstem processing, auditory gating and selective auditory attention. In contrast to PD, literature on central auditory processing in atypical parkinsonian disorders was relatively scarce, but provided some evidence for impaired central auditory processing in MSA and PSP. The interpretation of these findings is discussed and suggestions for further research are offered.