Chemotherapy-induced nausea in a sample of gynaecological cancer patients: assessment issues and personal risk factors evaluation

Purpose Chemotherapy-induced nausea (CIN) is a relevant problem for gynaecological cancer patients. The evaluation of CIN is a key aspect in its management, along with the identification of associated risk factors. The objective of the study was to compare different measurements of nausea and to inv...

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Veröffentlicht in:Supportive care in cancer 2020-11, Vol.28 (11), p.5343-5351
Hauptverfasser: Di Mattei, Valentina E., Carnelli, Letizia, Taranto, Paola, Mazzetti, Martina, Perego, Gaia, Rottoli, Sara, Rancoita, Paola M. V., Bergamini, Alice, Petrone, Micaela, Rabaiotti, Emanuela, Candotti, Giorgio, Candiani, Massimo
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Sprache:eng
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Zusammenfassung:Purpose Chemotherapy-induced nausea (CIN) is a relevant problem for gynaecological cancer patients. The evaluation of CIN is a key aspect in its management, along with the identification of associated risk factors. The objective of the study was to compare different measurements of nausea and to investigate personal risk factors in CIN development. Method Eighty-one women treated for gynaecological cancers took part. The presence of CIN was evaluated using the MASCC Antiemesis Tool (MAT) and a patient’s report to clinicians at the subsequent chemotherapy cycle. Personal risk factors were assessed using the State-Trait Anxiety Inventory and a self-report questionnaire. Results The study shows that the agreement between patients’ assessment of CIN with MAT and what they referred to clinicians was only moderate for acute nausea (Cohen’s Kappa = 0.55; p  
ISSN:0941-4355
1433-7339
1433-7339
DOI:10.1007/s00520-020-05377-1