Positive lymph node number and extranodal extension for predicting recurrence and survival in patients with salivary gland cancer

Positive lymph node number and extranodal extension for predicting recurrence and survival in patients with salivary gland cancer

Background This study compared our proposed N classification including the addition of the number of positive lymph node (LN+) and extranodal extension (ENE) with the current and previous American Joint Committee on Cancer (AJCC) N classifications in salivary gland cancer (SGC). Methods This study i...

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Veröffentlicht in:Head & neck 2020-08, Vol.42 (8), p.1994-2001
Hauptverfasser: Lee, Hojun, Roh, Jong‐Lyel, Cho, Kyung‐Ja, Choi, Seung‐Ho, Nam, Soon Yuhl, Kim, Sang Yoon
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Classification
extranodal extension
Head and neck
lymph node metastasis
Lymph nodes
Lymphatic system
N classification
Oral cancer
Patients
prognosis
Salivary gland
salivary gland cancer
Surgery
Survival
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Zusammenfassung:Background This study compared our proposed N classification including the addition of the number of positive lymph node (LN+) and extranodal extension (ENE) with the current and previous American Joint Committee on Cancer (AJCC) N classifications in salivary gland cancer (SGC). Methods This study involved 172 SGC patients who underwent surgery. Cox proportional hazard regression analyses were used to identify factors associated with overall survival (OS) and disease‐free survival (DFS). Results In multivariate analyses, LN+ number, LN ratio, and ENE were associated with OS and DFS outcomes (all P 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.26135