A sequence-specific plasmonic loop-mediated isothermal amplification assay with orthogonal color readouts enabled by CRISPR Cas12a

Herein, we introduce a sequence-specific plasmonic loop-mediated isothermal amplification (LAMP) assay with dual, complementary color readouts enabled by CRISPR Cas12a. Using this assay, any double-stranded LAMP amplicon containing a 5'-TTN PAM sequence can be recognized by Cas12a through a spe...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (24), p.3536-3538
Hauptverfasser:	Zhou, Rongxing, Li, Yongya, Dong, Tianyu, Tang, Yanan, Li, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Color CRISPR Signal transduction
Online-Zugang:	Volltext
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