Impact on Oncological Outcomes and Intent-to-Treat Survival of Resection Margin for Transplantable Hepatocellular Carcinoma in All-Comers and in Patients with Cirrhosis: A Multicenter Study

Background The outcomes of liver resection (LR) with a narrow margin in patients with transplantable hepatocellular carcinoma (HCC) have not been studied. The aim was to assess whether narrow margin following up-front LR impacts the incidence, timing, pattern, and transplantability of tumor recurren...

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Veröffentlicht in:World journal of surgery 2020-06, Vol.44 (6), p.1966-1974
Hauptverfasser: Lim, Chetana, Goumard, Claire, Casellas-Robert, Margarida, Lopez-Ben, Santiago, Lladó, Laura, Busquets, Juli, Salloum, Chady, Albiol-Quer, Maria Teresa, Castro-Gutiérrez, Ernest, Rosmorduc, Olivier, Feray, Cyrille, Ramos, Emilio, Figueras, Joan, Scatton, Olivier, Azoulay, Daniel
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Sprache:eng
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Zusammenfassung:Background The outcomes of liver resection (LR) with a narrow margin in patients with transplantable hepatocellular carcinoma (HCC) have not been studied. The aim was to assess whether narrow margin following up-front LR impacts the incidence, timing, pattern, and transplantability of tumor recurrence in patients with initially transplantable HCC. Methods All initially transplantable HCC patients undergoing hepatectomy with either narrow (
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-020-05424-2