3-(4-Methylbenzylidene) camphor induced reproduction toxicity and antiandrogenicity in Japanese medaka (Oryzias latipes)

To assess the toxic effects of 3-(4-Methylbenzylidene) camphor (4-MBC) at environmentally relevant concentrations on the reproduction and development of Japanese medaka (Oryzias latipes), adult paired medaka (F0) were exposed to 5, 50, and 500 μg/L 4-MBC for 28 d in the current study. The fecundity...

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Veröffentlicht in:	Chemosphere (Oxford) 2020-06, Vol.249, p.126224-126224, Article 126224
Hauptverfasser:	Liang, Mengmeng, Yan, Saihong, Chen, Rui, Hong, Xiangsheng, Zha, Jinmiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Camphor - analogs & derivatives Camphor - toxicity Development toxicity Endocrine disruption Female Fertility - drug effects Gonads - drug effects Histopathology Liver - drug effects Male Oryzias - physiology Reproduction - drug effects UV filter Vitellogenins Water Pollutants, Chemical - toxicity
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Beschreibung
Zusammenfassung:	To assess the toxic effects of 3-(4-Methylbenzylidene) camphor (4-MBC) at environmentally relevant concentrations on the reproduction and development of Japanese medaka (Oryzias latipes), adult paired medaka (F0) were exposed to 5, 50, and 500 μg/L 4-MBC for 28 d in the current study. The fecundity and fertility were significantly decreased at 500 μg/L 4-MBC (p
ISSN:	0045-6535 1879-1298
DOI:	10.1016/j.chemosphere.2020.126224