Recent advances in the application of layered double hydroxides in analytical chemistry: A review

In recent years, layered double hydroxides (LDHs) have garnered a lot of attention in analytical chemistry, due to their advantages such as relatively simple synthesis, low cost, possession of large specific surface area and high catalytic activity, and biocompatibility. The most common applications of LDH in analytical chemistry such as sorbents in sample extraction, electrode materials in electrochemical sensing and color indicators in colorimetric detection have been well reported. Generally, the LDHs are prepared as composites with nanomaterials, or constructed with specific three-dimensional structures, befitting the applications desired for them. However, the applications of LDHs (as extraction sorbents, color indicators and in electrochemical sensing) are usually limited in these scenarios. To help address these challenges, future trends and developmental prospects of LDHs materials in analytical chemistry are discussed in this article. Besides, the strategies associated with the design of LDHs, including the structural aspects, for potential analytical applications are presented and reviewed. [Display omitted] •A critical review of LDHs-based recent analytical applications are presented.•LDH composites with different structures are described.•The application of LDHs are categorized by types of analytes involved.•The strategies of LDH applications, future challenges are discussed.