Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy

[Display omitted] •Three branched N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose derivatives were synthesized.•The obtained compounds were conjugated to fluorescent dye sulfo-Cy5 alkyne.•By liver intravital microscopy, cellular uptake of the fluorescent glycoconjugates was tracked in real time.•GalNAc conjugate was taken up by hepatocytes, while GlcNAc and Man derivatives entered liver sinusoidal endothelial cells.