Daytime-restricted feeding modulates the expression of inflammatory mediators and diminishes reactive astrogliosis and microgliosis following status epilepticus

Daytime-restricted feeding modulates the expression of inflammatory mediators and diminishes reactive astrogliosis and microgliosis following status epilepticus

[Display omitted] •Inflammatory mediators are modulated by DRF.•DRF confers neuroprotection in CA1 and hilus regions of hippocampus.•Reactive astrogliosis is reduced by DRF after seizures.•DRF is able to reduce the microglia activation after status epilepticus.

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Veröffentlicht in:Brain research 2020-05, Vol.1734, p.146724-146724, Article 146724
Hauptverfasser: Santillán-Cigales, Juan Jair, Mercado-Gómez, Octavio Fabián, Arriaga-Ávila, Virginia, Landgrave-Gómez, Jorge, Guevara-Guzmán, Rosalinda
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Sprache:eng
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Zusammenfassung:[Display omitted] •Inflammatory mediators are modulated by DRF.•DRF confers neuroprotection in CA1 and hilus regions of hippocampus.•Reactive astrogliosis is reduced by DRF after seizures.•DRF is able to reduce the microglia activation after status epilepticus.
ISSN:0006-8993
1872-6240
DOI:10.1016/j.brainres.2020.146724