Reproductive toxicity and estrogen activity in Japanese medaka (Oryzias latipes) exposed to environmentally relevant concentrations of octocrylene

Reproductive toxicity and estrogen activity in Japanese medaka (Oryzias latipes) exposed to environmentally relevant concentrations of octocrylene

The growing use of octocrylene (OC) in sunscreens has posed a great threat to aquatic organisms. In the present study, to assess its reproductive toxicity and mechanism, paired Japanese medaka (Oryzias latipes) (F0) were exposed to OC at nominal concentrations of 5, 50, and 500 μg/L for 28 d. Signif...

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Veröffentlicht in:Environmental pollution (1987) 2020-06, Vol.261, p.114104-114104, Article 114104
Hauptverfasser: Yan, Saihong, Liang, Mengmeng, Chen, Rui, Hong, Xiangsheng, Zha, Jinmiao
Format: Artikel
Sprache:eng
Schlagworte:
Embryonic development
Endocrine disrupting
Histopathology
Japanese medaka (Oryzias latipes)
Octocrylene
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Zusammenfassung:The growing use of octocrylene (OC) in sunscreens has posed a great threat to aquatic organisms. In the present study, to assess its reproductive toxicity and mechanism, paired Japanese medaka (Oryzias latipes) (F0) were exposed to OC at nominal concentrations of 5, 50, and 500 μg/L for 28 d. Significant increases were observed in the gonadosomatic index (GSI) and hepatosomatic index (HSI) of F0 medaka at 500 μg/L OC (p 
ISSN:0269-7491
1873-6424
DOI:10.1016/j.envpol.2020.114104