Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome

Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: analysis of surgical outcome

Objectives We investigated the clinical significance of ACTH stimulation during adrenal venous sampling (AVS) by surgical outcome of primary aldosteronism (PA). Design Multicenter retrospective study by Japan PA study. Method We allocated 314 patients with both basal and ACTH-stimulated AVS data who...

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Veröffentlicht in:European journal of endocrinology 2020-03, Vol.182 (3), p.265-273
Hauptverfasser: Kobayashi, Hiroki, Nakamura, Yoshihiro, Abe, Masanori, Kurihara, Isao, Itoh, Hiroshi, Ichijo, Takamasa, Takeda, Yoshiyu, Yoneda, Takashi, Katabami, Takuyuki, Tsuiki, Mika, Wada, Norio, Ogawa, Yoshihiro, Sakamoto, Ryuichi, Kawashima, Junji, Sone, Masakatsu, Inagaki, Nobuya, Yoshimoto, Takanobu, Yamada, Tetsuya, Okamoto, Ryuji, Matsuda, Yuichi, Fujita, Megumi, Watanabe, Minemori, Tamura, Kouichi, Tanabe, Akiyo, Naruse, Mitsuhide
Format: Artikel
Sprache:eng
Schlagworte:
Adenoma
Adenoma - pathology
Adrenal Gland Neoplasms - pathology
Adrenal Glands - drug effects
Adrenal Glands - metabolism
Adrenalectomy
Adrenocortical Adenoma - pathology
Adrenocorticotropic hormone
Adult
Aged
Clinical Study
Cohort Studies
Cosyntropin - pharmacology
Endocrine disorders
Female
Humans
Hyperaldosteronism - surgery
Male
Middle Aged
Prognosis
Registries
Retrospective Studies
Sampling
Sensitivity and Specificity
Surgical outcomes
Treatment Outcome
Tumors
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Zusammenfassung:Objectives We investigated the clinical significance of ACTH stimulation during adrenal venous sampling (AVS) by surgical outcome of primary aldosteronism (PA). Design Multicenter retrospective study by Japan PA study. Method We allocated 314 patients with both basal and ACTH-stimulated AVS data who underwent adrenalectomy to three groups: basal lateralization index (LI) ≥2 with ACTH-stimulated LI ≥4 on the ipsilateral side (Unilateral (U) to U group, n = 245); basal LI
ISSN:0804-4643
1479-683X
DOI:10.1530/EJE-19-0860