Placebo and Nocebo Effects

Placebo and Nocebo Effects

Placebo and nocebo effects (effects of patients’ positive and negative expectations) are powerful and pervasive in clinical practice. Neurobiologic mechanisms, information offered about treatment, prior encounters with a drug or procedure, and the therapeutic milieu can all generate these effects.

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Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2020-02, Vol.382 (6), p.554-561
Hauptverfasser: Colloca, Luana, Barsky, Arthur J
Format: Artikel
Sprache:eng
Schlagworte:
Analgesics
Asthma
Clinical medicine
Clinical trials
Conditioning, Psychological
Dopamine
Drug dosages
Dyspnea
Health care
Humans
Hyperactivity
Hyperalgesia - etiology
Narcotics
Nervous System Physiological Phenomena
Nocebo Effect
Nocebos
Pain
Placebo Effect
Spinal cord
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Beschreibung
Zusammenfassung:Placebo and nocebo effects (effects of patients’ positive and negative expectations) are powerful and pervasive in clinical practice. Neurobiologic mechanisms, information offered about treatment, prior encounters with a drug or procedure, and the therapeutic milieu can all generate these effects.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMra1907805