Comparison of Fracture Prediction Tools in Individuals Without and With Early Chronic Kidney Disease: A Population‐Based Analysis of CARTaGENE

ABSTRACT Whether fracture prediction tools developed for the management of osteoporosis can be used in chronic kidney disease (CKD) is poorly known. We aimed to compare the performance of fracture prediction tools in non‐CKD and CKD. We analyzed CARTaGENE, a population‐based survey of 40‐year‐old to...

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Veröffentlicht in:	Journal of bone and mineral research 2020-06, Vol.35 (6), p.1048-1057
Hauptverfasser:	Desbiens, Louis‐Charles, Sidibé, Aboubacar, Beaudoin, Claudia, Jean, Sonia, Mac‐Way, Fabrice
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bone Density CHRONIC KIDNEY DISEASE CKD‐MBD Creatinine Discrimination FRACTURE RISK ASSESSMENT Fractures FRAX GARVAN Health risk assessment Humans Kidney diseases Middle Aged MINERAL AND BONE DISORDERS Osteoporosis Osteoporotic Fractures - epidemiology Predictions QFracture Renal function Renal Insufficiency, Chronic - epidemiology Risk Assessment Risk Factors Statistical analysis
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Zusammenfassung:	ABSTRACT Whether fracture prediction tools developed for the management of osteoporosis can be used in chronic kidney disease (CKD) is poorly known. We aimed to compare the performance of fracture prediction tools in non‐CKD and CKD. We analyzed CARTaGENE, a population‐based survey of 40‐year‐old to 69‐year‐old individuals recruited between 2009 and 2010. Renal function was assessed using baseline creatinine and categorized according to Kidney Disease Improving Global Outcomes (KDIGO) guidelines (non‐CKD, stage 2, stage 3). Individuals without creatinine measurements or with advanced CKD (stage 4 or 5; prevalence
ISSN:	0884-0431 1523-4681
DOI:	10.1002/jbmr.3977