Study on the relationship between FFA and gout flare

Objectives To detect the serum free fatty acid (FFA) concentration in patients with primary gouty arthritis (GA) and to explore the correlation between FFA and gout flare. Method Sixty patients with acute GA, 60 patients with GA remission, 60 patients with asymptomatic hyperuricemia (HUA), and 60 no...

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Veröffentlicht in:Clinical rheumatology 2020-04, Vol.39 (4), p.1251-1255
Hauptverfasser: Pei, Lin, Xie, Linfeng, Wu, Junying, Zhang, Han, Zhang, Xuewu
Format: Artikel
Sprache:eng
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Zusammenfassung:Objectives To detect the serum free fatty acid (FFA) concentration in patients with primary gouty arthritis (GA) and to explore the correlation between FFA and gout flare. Method Sixty patients with acute GA, 60 patients with GA remission, 60 patients with asymptomatic hyperuricemia (HUA), and 60 normal controls were enrolled in this study. Serum FFA concentration was detected by enzymatic determination in four groups, and the relationship between serum FFA, serum urate (SU), and other clinical and laboratory parameters was analyzed. Results (1) Serum FFA concentration was significantly higher in the acute GA than in the GA remission, the asymptomatic HUA, and the normal control ( H  = 72.191, P  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-019-04903-9