Metal-free visible-light-mediated organophotoredox catalysis: synthesis of 3-functionalized indole via C–C, C–N bond formation

Metal-free visible-light-mediated organophotoredox catalysis: synthesis of 3-functionalized indole via C–C, C–N bond formation

A visible-light-mediated, mild and one-pot three-component reaction in the presence of organophotoredox catalyst Eosin Y using EtOH:H 2 O as reaction medium for the synthesis of 3-functionalized indole derivatives was developed. Visible light used in the protocol is green, inexpensive, readily avail...

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Veröffentlicht in:Molecular diversity 2021-05, Vol.25 (2), p.1103-1109
Hauptverfasser: Yadav, Neetu, Ansari, Mohd Danish, Yadav, Vijay B., Verma, Ankit, Tiwari, Saurabh K., Ansari, Saif, Siddiqui, I. R.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Life Sciences
Organic Chemistry
Pharmacy
Polymer Sciences
Short Communication
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Zusammenfassung:A visible-light-mediated, mild and one-pot three-component reaction in the presence of organophotoredox catalyst Eosin Y using EtOH:H 2 O as reaction medium for the synthesis of 3-functionalized indole derivatives was developed. Visible light used in the protocol is green, inexpensive, readily available energy source. The sustainable reagents make the protocol compatible with green chemistry demands. Graphic Abstract
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-020-10044-y