Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens

Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens

T-cell recognizable p53 hotspot mutations offer opportunities for immunotherapy and immune monitoring. Recognition of p53 mutations by peripheral blood CD8 and CD4 T lymphocytes has been revealed. .

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Bibliographische Detailangaben
Veröffentlicht in:Clinical cancer research 2020-03, Vol.26 (6), p.1203-1204
Hauptverfasser: Olivera, Irene, Etxeberria, Iñaki, Bolaños, Elixabet, Gato-Cañas, María, Melero, Ignacio
Format: Artikel
Sprache:eng
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Zusammenfassung:T-cell recognizable p53 hotspot mutations offer opportunities for immunotherapy and immune monitoring. Recognition of p53 mutations by peripheral blood CD8 and CD4 T lymphocytes has been revealed. .
ISSN:1078-0432
1557-3265
DOI:10.1158/1078-0432.CCR-19-3813