Passive microwave radiometry in biomedical studies

•Passive medical microwave radiometry is a method of measuring the intensity of intrinsic emission from biological objects in the range 1–10GHz.•It gives opportunity to use the same readout in drug discovery, pre-clinical, clinical studies, monitor efficiency, and early diagnostics.•Internal (Deep, Brightness) Temperature is emission power (W) from human body or other biological objects converted to temperature in degrees.•Thermal asymmetry is a deep temperature difference between left and right side of the human body, specific tissue or organ. Passive microwave radiometry (MWR) measures natural emissions in the range 1–10GHz from proteins, cells, organs and the whole human body. The intensity of intrinsic emission is determined by biochemical and biophysical processes. The nature of this process is still not very well known. Infrared thermography (IRT) can detect emission several microns deep (skin temperature), whereas MWR allows detection of thermal abnormalities down to several centimeters (internal or deep temperature). MWR is noninvasive and inexpensive. It requires neither fluorescent nor radioactive labels, nor ionizing or other radiation. MWR can be used in early drug discovery as well as preclinical and clinical studies.