Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement

Intermediate-risk patients with aortic stenosis were randomly assigned to undergo either transcatheter or surgical aortic-valve replacement. At 5 years, there was no significant difference between the two groups in the incidence of death or disabling stroke. The incidence of aortic regurgitation was...

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Veröffentlicht in:	The New England journal of medicine 2020-02, Vol.382 (9), p.799-809
Hauptverfasser:	Makkar, Raj R, Thourani, Vinod H, Mack, Michael J, Kodali, Susheel K, Kapadia, Samir, Webb, John G, Yoon, Sung-Han, Trento, Alfredo, Svensson, Lars G, Herrmann, Howard C, Szeto, Wilson Y, Miller, D. Craig, Satler, Lowell, Cohen, David J, Dewey, Todd M, Babaliaros, Vasilis, Williams, Mathew R, Kereiakes, Dean J, Zajarias, Alan, Greason, Kevin L, Whisenant, Brian K, Hodson, Robert W, Brown, David L, Fearon, William F, Russo, Mark J, Pibarot, Philippe, Hahn, Rebecca T, Jaber, Wael A, Rogers, Erin, Xu, Ke, Wheeler, Jaime, Alu, Maria C, Smith, Craig R, Leon, Martin B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aortic stenosis Aortic Valve - diagnostic imaging Aortic Valve - surgery Aortic Valve Insufficiency - etiology Aortic Valve Insufficiency - physiopathology Aortic Valve Stenosis - complications Aortic Valve Stenosis - diagnostic imaging Aortic Valve Stenosis - mortality Aortic Valve Stenosis - surgery Cardiovascular disease Clinical outcomes Cohort Studies Committees Confidence intervals Coronary vessels Death Echocardiography Female Health Status Heart Heart Valve Prosthesis Heart Valve Prosthesis Implantation - methods Humans Incidence Intention to Treat Analysis Kaplan-Meier Estimate Laboratories Male Multivariate Analysis Ostomy Patients Postoperative Complications - mortality Regurgitation Risk Factors Statistical analysis Stenosis Stroke Stroke - epidemiology Stroke - etiology Surgery Transcatheter Aortic Valve Replacement Treatment Outcome
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Zusammenfassung:	Intermediate-risk patients with aortic stenosis were randomly assigned to undergo either transcatheter or surgical aortic-valve replacement. At 5 years, there was no significant difference between the two groups in the incidence of death or disabling stroke. The incidence of aortic regurgitation was higher with transcatheter AVR.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1910555