Rotavirus vaccination impact, Ireland, implications for vaccine confidence and screening

Abstract Background Rotavirus vaccine efficacy is well established. However, it is important to consistently demonstrate the positive impact of vaccination programmes in order to optimize uptake rates and combat vaccine hesitancy. Methods Routine data were used to examine rotavirus vaccine effective...

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Veröffentlicht in:European journal of public health 2020-04, Vol.30 (2), p.281-285
Hauptverfasser: Burns, Heather E, Collins, Abigail M, Fallon, Una B, Marsden, Paul V, Ni Shuilleabhain, Caitlin M
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Sprache:eng
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Zusammenfassung:Abstract Background Rotavirus vaccine efficacy is well established. However, it is important to consistently demonstrate the positive impact of vaccination programmes in order to optimize uptake rates and combat vaccine hesitancy. Methods Routine data were used to examine rotavirus vaccine effectiveness in Ireland, including changes in age-specific crude incidence rates (CIRs), hospitalizations and hospital length of stay. National intussusception incidence was interrogated. Vaccination status of vaccine-eligible cases of rotavirus infection was determined. Results Nationally, a reduction in the CIR of rotavirus infection of 77.2% [95% confidence interval (CI) 57.8–88.5%, P
ISSN:1101-1262
1464-360X
DOI:10.1093/eurpub/ckz238