Fool’s gold? Why blinded trials are not always best

Blinding is intended to reduce bias but can make studies unnecessarily complex or lead to results that no longer address the clinical question, argue Rohan Anand and colleagues

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Bibliographische Detailangaben
Veröffentlicht in:	BMJ (Online) 2020-01, Vol.368, p.l6228-l6228
Hauptverfasser:	Anand, Rohan, Norrie, John, Bradley, Judy M, McAuley, Danny F, Clarke, Mike
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bias Clinical trials Clinical Trials as Topic - organization & administration Clinical Trials as Topic - standards Criminal investigations Data Accuracy Design Double-Blind Method Humans Intervention Observer Variation Outcome Assessment, Health Care - methods Outcome Assessment, Health Care - standards Patient Safety Randomized Controlled Trials as Topic - methods Research Design - standards Researchers Retention Stroke
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Beschreibung
Zusammenfassung:	Blinding is intended to reduce bias but can make studies unnecessarily complex or lead to results that no longer address the clinical question, argue Rohan Anand and colleagues
ISSN:	1756-1833 1756-1833
DOI:	10.1136/bmj.l6228