‘Bohemian Rhapsody’ of MR1T cells

‘Bohemian Rhapsody’ of MR1T cells

A T cell recognizing the MHC class I–related molecule MR1, expressed by a wide range of cancer cell types, might have great potential for adoptive cell therapy in cancer.

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Bibliographische Detailangaben
Veröffentlicht in:Nature immunology 2020-02, Vol.21 (2), p.108-110
Hauptverfasser: Mori, Lucia, De Libero, Gennaro
Format: Artikel
Sprache:eng
Schlagworte:
631/250/1619/554/1775
631/250/2504
631/250/580
631/67/1059/2325
Biomedical and Life Sciences
Biomedicine
Cancer
Care and treatment
Cell therapy
Clustered Regularly Interspaced Short Palindromic Repeats
CRISPR-Cas Systems
Early Detection of Cancer
Histocompatibility Antigens Class I
Immunology
Immunotherapy
Infectious Diseases
Lymphocytes
Lymphocytes T
Major histocompatibility complex
News & Views
news-and-views
T cells
T-Lymphocytes
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Beschreibung
Zusammenfassung:A T cell recognizing the MHC class I–related molecule MR1, expressed by a wide range of cancer cell types, might have great potential for adoptive cell therapy in cancer.
ISSN:1529-2908
1529-2916
DOI:10.1038/s41590-019-0588-6