Cross-sectional study of hepatitis B antibody status in health care workers immunized as children at an academic medical center in Wisconsin

Cross-sectional study of hepatitis B antibody status in health care workers immunized as children at an academic medical center in Wisconsin

•Sustained hepatitis B protection in 95% of healthcare workers immunized as infants.•Males and infants younger than 7 months more likely to be vaccine non-responders.•Consider a policy using hepatitis B vaccine series history as evidence of immunity. Individuals who received the hepatitis B vaccine...

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Veröffentlicht in:Vaccine 2020-02, Vol.38 (7), p.1597-1600
Hauptverfasser: Ritscher, Alicia M., LeClair-Netzel, Megan, Friedlander, Nicholas J., Howard Stewart, Danielle N., Wagner, Mallory, Kalscheur, Nicole, Caldera, Freddy, Hayney, Mary S.
Format: Artikel
Sprache:eng
Schlagworte:
Academic Medical Centers
Adult
Age
Anamnestic response
Anti-HBs
Antibodies
Antigens
Bloodborne pathogen
Children
Cross-Sectional Studies
Documentation
Employees
Female
Health care
Health care facilities
Health care workers
Health Personnel
Health services
Hepatitis
Hepatitis B
Hepatitis B - prevention & control
Hepatitis B Antibodies - blood
Hepatitis B surface antigen
Hepatitis B Surface Antigens
Hepatitis B vaccine
Hepatitis B Vaccines - administration & dosage
Humans
Immune response
Immunization
Immunization, Secondary
Immunologic Memory
Male
Medical personnel
Seroepidemiologic Studies
Vaccination
Vaccines
Wisconsin
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Beschreibung
Zusammenfassung:•Sustained hepatitis B protection in 95% of healthcare workers immunized as infants.•Males and infants younger than 7 months more likely to be vaccine non-responders.•Consider a policy using hepatitis B vaccine series history as evidence of immunity. Individuals who received the hepatitis B vaccine series as young children are entering the healthcare workforce. Our study measured the persistence of antibody to the hepatitis B surface antigen (anti-HBs) at time of employment. Among 986 individuals born in 1991 or more recently with documentation of completion of the hepatitis B vaccine series, 51% had anti-HBs 
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2019.12.036