Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides

This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Archives of dermatology (1960) 2019-09, Vol.155 (9), p.1084-1086
Hauptverfasser: Nguyen, Anh Ly, Morren, Marie-Anne, van Doorn, Remco
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1086
container_issue 9
container_start_page 1084
container_title Archives of dermatology (1960)
container_volume 155
creator Nguyen, Anh Ly
Morren, Marie-Anne
van Doorn, Remco
description This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.
doi_str_mv 10.1001/jamadermatol.2019.1404
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2340044213</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ama_id>2736965</ama_id><sourcerecordid>2340044213</sourcerecordid><originalsourceid>FETCH-LOGICAL-a358t-f222b05ba2a0e0d6ce32b2c3ca13b2e47778be1bf01fdff21966962d94a5038c3</originalsourceid><addsrcrecordid>eNpdkcFqGzEQhkVoiE2SF8ghLPTSi13NSN5dH41pkoLBhbTnRVrNOjJayZV2W_z2lXFqSucyA_P9w8z8jD0CnwPn8HmvemUo9moIbo4clnOQXF6xKUJZz0peyw-Xuqwn7D6lPc9Rcy4F3LCJAJRQoZwy_Uq_KFKxsYdgjmmI4fB2LJ6Cc-G39bviWwwu-B2Z4nXU7TgoT2FMxcr01tuMq8EGX4SuWPnBJvKJiq2zu-DH1lEYrKF0x6475RLdv-db9uPpy_f1y2yzff66Xm1mSizqYdYhouYLrVBx4qZsSaDGVrQKhEaSVVXVmkB3HDrTdQjLslyWaJZSLbioW3HLPp3nHmL4OVIamt6mlpw779ygkPl-iSAy-vE_dB_G6PN2meIoEaGCTJVnqo0hpUhdc4i2V_HYAG9ORjT_GtGcjGhORmTh4_v4UfdkLrK_b8_AwxnI-ksXK5EPWog_ygORhA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2302422171</pqid></control><display><type>article</type><title>Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides</title><source>AMA_美国医学会期刊</source><creator>Nguyen, Anh Ly ; Morren, Marie-Anne ; van Doorn, Remco</creator><creatorcontrib>Nguyen, Anh Ly ; Morren, Marie-Anne ; van Doorn, Remco</creatorcontrib><description>This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.</description><identifier>ISSN: 2168-6068</identifier><identifier>EISSN: 2168-6084</identifier><identifier>DOI: 10.1001/jamadermatol.2019.1404</identifier><identifier>PMID: 31241724</identifier><language>eng</language><publisher>United States: American Medical Association</publisher><subject>Medical treatment ; Muscular dystrophy ; Neuromuscular diseases ; Pediatrics</subject><ispartof>Archives of dermatology (1960), 2019-09, Vol.155 (9), p.1084-1086</ispartof><rights>Copyright American Medical Association Sep 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a358t-f222b05ba2a0e0d6ce32b2c3ca13b2e47778be1bf01fdff21966962d94a5038c3</citedby><cites>FETCH-LOGICAL-a358t-f222b05ba2a0e0d6ce32b2c3ca13b2e47778be1bf01fdff21966962d94a5038c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamadermatology/articlepdf/10.1001/jamadermatol.2019.1404$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2019.1404$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,780,784,3340,27924,27925,76489,76492</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31241724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nguyen, Anh Ly</creatorcontrib><creatorcontrib>Morren, Marie-Anne</creatorcontrib><creatorcontrib>van Doorn, Remco</creatorcontrib><title>Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides</title><title>Archives of dermatology (1960)</title><addtitle>JAMA Dermatol</addtitle><description>This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.</description><subject>Medical treatment</subject><subject>Muscular dystrophy</subject><subject>Neuromuscular diseases</subject><subject>Pediatrics</subject><issn>2168-6068</issn><issn>2168-6084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdkcFqGzEQhkVoiE2SF8ghLPTSi13NSN5dH41pkoLBhbTnRVrNOjJayZV2W_z2lXFqSucyA_P9w8z8jD0CnwPn8HmvemUo9moIbo4clnOQXF6xKUJZz0peyw-Xuqwn7D6lPc9Rcy4F3LCJAJRQoZwy_Uq_KFKxsYdgjmmI4fB2LJ6Cc-G39bviWwwu-B2Z4nXU7TgoT2FMxcr01tuMq8EGX4SuWPnBJvKJiq2zu-DH1lEYrKF0x6475RLdv-db9uPpy_f1y2yzff66Xm1mSizqYdYhouYLrVBx4qZsSaDGVrQKhEaSVVXVmkB3HDrTdQjLslyWaJZSLbioW3HLPp3nHmL4OVIamt6mlpw779ygkPl-iSAy-vE_dB_G6PN2meIoEaGCTJVnqo0hpUhdc4i2V_HYAG9ORjT_GtGcjGhORmTh4_v4UfdkLrK_b8_AwxnI-ksXK5EPWog_ygORhA</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Nguyen, Anh Ly</creator><creator>Morren, Marie-Anne</creator><creator>van Doorn, Remco</creator><general>American Medical Association</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20190901</creationdate><title>Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides</title><author>Nguyen, Anh Ly ; Morren, Marie-Anne ; van Doorn, Remco</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a358t-f222b05ba2a0e0d6ce32b2c3ca13b2e47778be1bf01fdff21966962d94a5038c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Medical treatment</topic><topic>Muscular dystrophy</topic><topic>Neuromuscular diseases</topic><topic>Pediatrics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nguyen, Anh Ly</creatorcontrib><creatorcontrib>Morren, Marie-Anne</creatorcontrib><creatorcontrib>van Doorn, Remco</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of dermatology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nguyen, Anh Ly</au><au>Morren, Marie-Anne</au><au>van Doorn, Remco</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides</atitle><jtitle>Archives of dermatology (1960)</jtitle><addtitle>JAMA Dermatol</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>155</volume><issue>9</issue><spage>1084</spage><epage>1086</epage><pages>1084-1086</pages><issn>2168-6068</issn><eissn>2168-6084</eissn><abstract>This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.</abstract><cop>United States</cop><pub>American Medical Association</pub><pmid>31241724</pmid><doi>10.1001/jamadermatol.2019.1404</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 2168-6068
ispartof Archives of dermatology (1960), 2019-09, Vol.155 (9), p.1084-1086
issn 2168-6068
2168-6084
language eng
recordid cdi_proquest_miscellaneous_2340044213
source AMA_美国医学会期刊
subjects Medical treatment
Muscular dystrophy
Neuromuscular diseases
Pediatrics
title Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T10%3A06%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Severe%20Lipodystrophy%20Following%20Prolonged%20Subcutaneous%20Administration%20of%20Antisense%20Oligonucleotides&rft.jtitle=Archives%20of%20dermatology%20(1960)&rft.au=Nguyen,%20Anh%20Ly&rft.date=2019-09-01&rft.volume=155&rft.issue=9&rft.spage=1084&rft.epage=1086&rft.pages=1084-1086&rft.issn=2168-6068&rft.eissn=2168-6084&rft_id=info:doi/10.1001/jamadermatol.2019.1404&rft_dat=%3Cproquest_cross%3E2340044213%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2302422171&rft_id=info:pmid/31241724&rft_ama_id=2736965&rfr_iscdi=true