Personalized goal for insomnia and clinical response in advanced cancer patients

Aim The aim of this study was to assess the Personalized Insomnia Intensity Goal (PIIG), the achievement of Personalized Goal Response (PGR), and Patient Global Impression (PGI) after a comprehensive symptom management. Patients and methods Advanced cancer patients admitted to palliative care units...

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Veröffentlicht in:Supportive care in cancer 2020-03, Vol.28 (3), p.1089-1096
Hauptverfasser: Mercadante, Sebastiano, Adile, Claudio, Aielli, Federica, Gaetano, Lanzetta, Mistakidou, Kyriaki, Maltoni, Marco, Cortegiani, Andrea, Soares, Luiz Guilherme, De Santis, Stefano, Ferrera, Patrizia, Rosati, Marta, Rossi, Romina, Casuccio, Alessandra
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Sprache:eng
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Zusammenfassung:Aim The aim of this study was to assess the Personalized Insomnia Intensity Goal (PIIG), the achievement of Personalized Goal Response (PGR), and Patient Global Impression (PGI) after a comprehensive symptom management. Patients and methods Advanced cancer patients admitted to palliative care units rated pain and symptoms intensity and their PIIG by using the Edmonton Symptom Assessment Score (ESAS) (T0). In patients with significant levels of insomnia, the achievement of target expected (PIIG) was measured (patient goal response, PIGR), as well the patient global impression (PGI), by the minimal clinically important difference (MCID), after a comprehensive symptom management (T7). Results Three hundred ninety-seven patients with a level of insomnia of ≥ 3 on ESAS were analyzed in this study. The mean values of PIIG at T0 and T7 were 1.2 (SD 1.5) and 0.9 (SD 1.4), respectively. Most patients ( n  = 406, 89.8%) indicated a PIIG of ≤ 3 as a target at T0. Such target was significantly lower at T7 ( p  = 
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-019-04912-z