Body mass index as a tool for optimizing surgical care in coronary artery bypass grafting through understanding risks of specific complications

To investigate the relationship between body mass index (BMI) and early outcomes, and specific types of morbidities associated with low and high BMI, in patients undergoing coronary artery bypass grafting. This was a retrospective study on isolated coronary artery bypass grafting patients (aged ≥60 ...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2020-08, Vol.160 (2), p.409-420.e14
Hauptverfasser: Nishioka, Naritomo, Ichihara, Nao, Bando, Ko, Motomura, Noboru, Koyama, Nobuya, Miyata, Hiroaki, Kohsaka, Shun, Takamoto, Shinichi, Hashimoto, Kazuhiro
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Sprache:eng
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Zusammenfassung:To investigate the relationship between body mass index (BMI) and early outcomes, and specific types of morbidities associated with low and high BMI, in patients undergoing coronary artery bypass grafting. This was a retrospective study on isolated coronary artery bypass grafting patients (aged ≥60 years) between 2008 and 2017 in the Japan Cardiovascular Surgery Database. The primary end point was defined as operative mortality. The secondary end point was combined morbidity (ie, operative mortality, reoperation for bleeding, stroke, new onset of hemodialysis, mediastinitis, and prolonged ventilation). Patient characteristics and outcomes were compared among BMI groups. Spline curves were fit between BMI and outcomes. Multivariable logistic regression models with categorized BMI and generalized additive models with spline-transformed BMI were used to estimate and visualize the effect of BMI adjusted for other covariates. A total of 96,058 patients were included in the analysis. Low (
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2019.07.048