Evolution of the Norwood operation outcomes in patients with late presentation

We present the evolution of Norwood operation outcomes and practice pattern changes over 15 years from a single institution in Saudi Arabia. We intended to identify time trends in patient selection, procedural details, and outcome predictors over time. Patients who underwent a Norwood operation (n =...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2020-03, Vol.159 (3), p.1040-1048
Hauptverfasser: Ismail, Mohamed F., Elmahrouk, Ahmed F., Arafat, Amr A., Hamouda, Tamer E., Alshaikh, Bayan A., Shihata, Mohammad S., Jamjoom, Ahmed A., Al-Radi, Osman O.
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Sprache:eng
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Zusammenfassung:We present the evolution of Norwood operation outcomes and practice pattern changes over 15 years from a single institution in Saudi Arabia. We intended to identify time trends in patient selection, procedural details, and outcome predictors over time. Patients who underwent a Norwood operation (n = 145) between 2003 and 2018 with the use of a Blalock–Taussig shunt (BT group; n = 72), right ventricle to pulmonary artery shunt (Sano group; n = 66), or a primary cavopulmonary shunt (CPS group; n = 7) were included. The study outcomes were operative mortality, long-term survival, and multistate transition to CPS, Fontan, and death. Median age was 29 days. Predictors of operative mortality were lower weight (P = .026), and longer bypass time (P = .014), whereas age, and type of shunt were not. Predictors of improved long-term survival were greater weight at operation (P = .0016), later era (P = .006), and shorter bypass time (P = .001). The multistate model revealed that patients with lower weight were more likely to undergo Sano versus BT (P 
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2019.07.154