Cytological diagnosis of juvenile xanthogranuloma: A rare histiocytic disorder

Juvenile xanthogranuloma (JXG) is a rare type of non‐Langerhan cell histiocytic disorder, which is mostly confined to skin of head and neck. It is a self‐limiting benign condition, which does not require surgery. We present a case of 8‐month‐old girl child with multiple yellowish brown colored papules over scalp, face, and neck. A clinical diagnosis of cutaneous mastocytosis was made. Fine‐needle aspiration cytology (FNAC) smears showed foamy macrophages along with mixed inflammatory infiltrate and few touton giant cells. A diagnosis of JXG was rendered which was confirmed on histopathology and immunohistochemistry.Juvenile xanthogranuloma can be diagnosed on FNAC based on its characteristic cytologic features; however, it requires a high index of suspicion by cytopathologist. Cytological diagnosis of JXG can save the patient from unnecessary surgical biopsy or excision.