Identification of Multiple Sclerosis key genetic factors through multi-staged data mining

Identification of Multiple Sclerosis key genetic factors through multi-staged data mining

•Mining through available multiple sclerosis expression data reveal novel findings.•MiRNA based gene-expression regulatory could affect the T-cell migration into BBB.•Targeting the obtained genetic factors may be effective to eliminate MS related signs.

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Veröffentlicht in:Multiple sclerosis and related disorders 2020-04, Vol.39, p.101446-101446, Article 101446
Hauptverfasser: Navaderi, Mohammad, Rajaei, Saeideh, Rahimirad, Samira, Jafari Harandi, Aysan, Ghaleh, Zahra, Falahati, Kowsar, Behgar, Zahra, Sedigh, Alireza Mirzaee, Sanati, Mohammad Hossein
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Sprache:eng
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Zusammenfassung:•Mining through available multiple sclerosis expression data reveal novel findings.•MiRNA based gene-expression regulatory could affect the T-cell migration into BBB.•Targeting the obtained genetic factors may be effective to eliminate MS related signs.
ISSN:2211-0348
2211-0356
DOI:10.1016/j.msard.2019.101446