Risk factors for acute kidney injury in critically ill patients with bacteraemia by carbapenem non-susceptible Gram negative bacteria

Risk factors for acute kidney injury in critically ill patients with bacteraemia by carbapenem non-susceptible Gram negative bacteria

The objectives of the present study were to identify risk factors for development of acute kidney injury (AKI) during the treatment of bacteraemia due to carbapenem non-susceptible Gram-negative bacteria (CnS-GNB) and its role on mortality. Data of all patients with bacteraemia by CnS-GNB in the int...

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Veröffentlicht in:Le infezioni in medicina 2019-12, Vol.27 (4), p.380-392
Hauptverfasser: Papadimitriou-Olivgeris, Matthaios, Assimakopoulos, Stelios F, Kolonitsiou, Fevronia, Solomou, Anastasia, Vamvakopoulou, Sophia, Spyropoulou, Aikaterini, Karamouzos, Vasileios, Anastassiou, Evangelos D, Papachristou, Evangelos, Spiliopoulou, Iris, Christofidou, Myrto, Fligou, Fotini, Marangos, Markos
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Sprache:eng
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Zusammenfassung:The objectives of the present study were to identify risk factors for development of acute kidney injury (AKI) during the treatment of bacteraemia due to carbapenem non-susceptible Gram-negative bacteria (CnS-GNB) and its role on mortality. Data of all patients with bacteraemia by CnS-GNB in the intensive care unit of a tertiary hospital from 2012 to 2016 were included. AKI was defined by AKIN criteria. Secondary outcomes were AKI development in patients treated with colistin and predictors of 14-day mortality. Among 285 episodes of bacteraemia due to CnS-GNB, 84 (29.5%) developed AKI. Multivariate analysis revealed that obesity, septic shock, maximum noradrenaline dose and eGFR
ISSN:1124-9390