Paediatric Buruli ulcer in Australia

Aim This study describes an Australian cohort of paediatric Buruli ulcer (BU) patients and compares them with adult BU patients. Methods Analysis of a prospective cohort of all BU cases managed at Barwon Health, Victoria, from 1 January 1998 to 31 May 2018 was performed. Children were defined as ≤15...

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Veröffentlicht in:	Journal of paediatrics and child health 2020-04, Vol.56 (4), p.636-641
Hauptverfasser:	Walker, Georgia, Friedman, Deborah N, O'Brien, Matthew P, Cooper, Chris, McDonald, Anthony, Callan, Peter, O'Brien, Daniel P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anti-Bacterial Agents - therapeutic use Antibiotics Australia Bacterial infections Buruli ulcer Buruli Ulcer - diagnosis Buruli Ulcer - drug therapy Buruli Ulcer - epidemiology Child Child, Preschool Female Humans Male Middle Aged Mycobacterium ulcerans paediatrics paradoxical reaction Pediatrics Prospective Studies Skin diseases Ulcers Victoria - epidemiology Young Adult
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Beschreibung
Zusammenfassung:	Aim This study describes an Australian cohort of paediatric Buruli ulcer (BU) patients and compares them with adult BU patients. Methods Analysis of a prospective cohort of all BU cases managed at Barwon Health, Victoria, from 1 January 1998 to 31 May 2018 was performed. Children were defined as ≤15 years of age. Results A total of 565 patients were included: 52 (9.2%) children, 289 (51.2%) adults aged 16–64 years and 224 (39.6%) adults aged ≥65 years. Among children, half were female and the median age was 8.0 years (interquartile range 4.8–12.3 years). Six (11.5%) cases were diagnosed from 2001 to 2006, 14 (26.9%) from 2007 to 2012 and 32 (61.5%) from 2013 to 2018. Compared to adults, children had a significantly higher proportion of non‐ulcerative lesions (32.7%, P
ISSN:	1034-4810 1440-1754
DOI:	10.1111/jpc.14704