Does celiac disease impair coronary microvascular circulation: Coronary flow velocity reserve of patients with celiac disease

Background Celiac disease (CD) is an enteropathy characterized with immune reaction to gliadin protein. Aim In this study, we aimed to assess effect of CD on coronary microvascular circulation and the association between coronary flow velocity reserve (CFVR) and hs‐CRP/Albumin ratio. Material and Me...

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Veröffentlicht in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-01, Vol.37 (1), p.34-40
Hauptverfasser: Caliskan, Zuhal, Telci Caklili, Ozge, Kahraman, Resul, Ozcan, Fatma Betul, Sayar, Suleyman, Kostek, Osman, Demircioglu, Kenan, Yilmaz, Yusuf, Kul, Seref, Caliskan, Mustafa
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Sprache:eng
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Zusammenfassung:Background Celiac disease (CD) is an enteropathy characterized with immune reaction to gliadin protein. Aim In this study, we aimed to assess effect of CD on coronary microvascular circulation and the association between coronary flow velocity reserve (CFVR) and hs‐CRP/Albumin ratio. Material and Methods Study was conducted between March 2017 and November 2018 with CD at Umraniye Training and Research Hospital Gastroenterology Clinic. CFVR was defined as the ratio of hyperemic to baseline diastolic peak velocities. CFVR ≥ 2.0 was considered normal. C‐reactive protein/albumin ratio (CAR) was calculated as hs‐CRP/albumin. Results Serum albumin (4.27 ± 0.56 vs 4.50 ± 0.34; P value: .04) level was significantly lower in celiac group but higher Hs‐CRP (2.44 ± 1.24 vs 1.82 ± 1.29; P value 
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.14554