Safety and tolerability of adjunctive brivaracetam in children with focal seizures: Interim analysis of pooled data from two open-label trials

Safety and tolerability of adjunctive brivaracetam in children with focal seizures: Interim analysis of pooled data from two open-label trials

To evaluate long-term safety and tolerability of adjunctive brivaracetam (BRV) in children with epilepsy. This was an interim analysis (cut-off March 15, 2017) of pooled data from two open-label, single-arm, multicentre trials. N01263 (NCT00422422) was a 3-week trial of BRV 0.8–4 mg/kg/day in patien...

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Veröffentlicht in:European journal of paediatric neurology 2020-03, Vol.25, p.68-76
Hauptverfasser: Patel, Anup D., Badalamenti, Vincent, Gasalla, Teresa, Elmoufti, Sami, Elshoff, Jan-Peer
Format: Artikel
Sprache:eng
Schlagworte:
Antiepileptic drug
Epilepsy syndrome
Focal seizure
Paediatric
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Beschreibung
Zusammenfassung:To evaluate long-term safety and tolerability of adjunctive brivaracetam (BRV) in children with epilepsy. This was an interim analysis (cut-off March 15, 2017) of pooled data from two open-label, single-arm, multicentre trials. N01263 (NCT00422422) was a 3-week trial of BRV 0.8–4 mg/kg/day in patients (1 month–
ISSN:1090-3798
1532-2130
DOI:10.1016/j.ejpn.2019.11.007