Fluorinated carboxylic acids as powerful building blocks for the formation of bimolecular monolayers

We compare the ability of a prototypical dicarboxylic acid and its fluorinated analogue to act as molecular building blocks for the formation of self-assembled monolayers. Whilst fluorination is found to prevent homomolecular self-assembly, it greatly increases the ability of the carboxylic acid to act as a hydrogen bond donor for the formation of bimolecular networks. Fluorination transforms a simple carboxylic acid into a highly effective building block for the formation of bimolecular monolayers.