A Strategy for the Synthesis of Sulfonamides on DNA
An efficient method is reported to synthesize sulfonamides on DNA from sulfinic acids or sodium sulfinates and amines in the presence of iodine under mild conditions. This method demonstrates a major expansion of scope of sulfonamide formation on DNA through the utilization of a novel sodium carbona...
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| Veröffentlicht in: | Organic letters 2019-12, Vol.21 (24), p.9909-9913 |
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| container_end_page | 9913 |
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| container_issue | 24 |
| container_start_page | 9909 |
| container_title | Organic letters |
| container_volume | 21 |
| creator | Liu, Wei Deng, Wei Sun, Saisai Yu, Chunyan Su, Xubo Wu, Aliang Yuan, Youlang Ma, Zhonglin Li, Ke Yang, Hongfang Peng, Xuanjia Dietrich, Justin |
| description | An efficient method is reported to synthesize sulfonamides on DNA from sulfinic acids or sodium sulfinates and amines in the presence of iodine under mild conditions. This method demonstrates a major expansion of scope of sulfonamide formation on DNA through the utilization of a novel sodium carbonate–sodium sulfinate bifunctional reagent class. |
| doi_str_mv | 10.1021/acs.orglett.9b03843 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2019-12, Vol.21 (24), p.9909-9913 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2320641115 |
| source | ACS Publications; MEDLINE |
| subjects | Amines - chemistry DNA - chemistry Iodine - chemistry Molecular Structure Sulfinic Acids - chemistry Sulfonamides - chemical synthesis Sulfonamides - chemistry |
| title | A Strategy for the Synthesis of Sulfonamides on DNA |
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