Supplemental MRI Screening for Women with Extremely Dense Breast Tissue

In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. There was a 50% lower rate of interval cancers among the women invited for MRI screening. Among those who underwent MRI-directed bio...

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Veröffentlicht in:	The New England journal of medicine 2019-11, Vol.381 (22), p.2091-2102
Hauptverfasser:	Bakker, Marije F, de Lange, Stéphanie V, Pijnappel, Ruud M, Mann, Ritse M, Peeters, Petra H.M, Monninkhof, Evelyn M, Emaus, Marleen J, Loo, Claudette E, Bisschops, Robertus H.C, Lobbes, Marc B.I, de Jong, Matthijn D.F, Duvivier, Katya M, Veltman, Jeroen, Karssemeijer, Nico, de Koning, Harry J, van Diest, Paul J, Mali, Willem P.T.M, van den Bosch, Maurice A.A.J, Veldhuis, Wouter B, van Gils, Carla H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biopsy Breast - diagnostic imaging Breast - pathology Breast cancer Breast Density Breast Neoplasms - diagnostic imaging Breast Neoplasms - epidemiology Early Detection of Cancer - methods False Positive Reactions Female Follow-Up Studies Humans Magnetic Resonance Imaging Mammography Medical research Middle Aged Mortality NMR Nuclear magnetic resonance R&D Research & development Risk factors Sensitivity and Specificity Software Womens health
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Beschreibung
Zusammenfassung:	In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. There was a 50% lower rate of interval cancers among the women invited for MRI screening. Among those who underwent MRI-directed biopsies, 26% had breast cancer.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1903986