Monoclonal Antibody Therapy for Ebola Virus Disease

Monoclonal Antibody Therapy for Ebola Virus Disease

Early reports in 1976 and 1995 documented cases in the Democratic Republic of Congo (DRC) of what we now know to be Ebola virus disease (EVD) caused by Zaire ebolavirus . The reports showed high case fatality rates and a propensity for transmission to close contacts such as family members caring for...

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Veröffentlicht in:The New England journal of medicine 2019-12, Vol.381 (24), p.2365-2366
1. Verfasser: Levine, Myron M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies, Monoclonal
Clinical trials
Ebola virus
Ebolavirus
Ebolavirus - immunology
Epidemics
Fatalities
Glycoproteins
Hemorrhagic Fever, Ebola
Immunoglobulins
Immunotherapy
Medical personnel
Monoclonal antibodies
Outbreaks
Respiratory diseases
Viral infections
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Beschreibung
Zusammenfassung:Early reports in 1976 and 1995 documented cases in the Democratic Republic of Congo (DRC) of what we now know to be Ebola virus disease (EVD) caused by Zaire ebolavirus . The reports showed high case fatality rates and a propensity for transmission to close contacts such as family members caring for ill relatives or health care workers caring for sick patients. The West African Z. ebolavirus outbreak of 2013–2016 that resulted in approximately 29,000 cases and about 11,000 deaths showed how extensive transmission can be when the virus is introduced into crowded urban areas. An outbreak of EVD in the . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMe1915350