Rheumatoid arthritis and risk of spontaneous abortion: a Danish nationwide cohort study

Rheumatoid arthritis and risk of spontaneous abortion: a Danish nationwide cohort study

Abstract Objectives To investigate the influence of RA or preclinical RA on the risk of spontaneous abortion (SA) while taking age and duration of RA into consideration. Methods By linkage of data from Danish national registries, we established a nationwide cohort of pregnancies in Denmark from 1 Ja...

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Veröffentlicht in:Rheumatology (Oxford, England) England), 2020-08, Vol.59 (8), p.1984-1991
Hauptverfasser: Nathan, Nina O, Mørch, Lina S, Wu, Chun S, Olsen, Jørn, Hetland, Merete L, Li, Jiong, Rom, Ane L
Format: Artikel
Sprache:eng
Schlagworte:
Abortion, Spontaneous - epidemiology
Abortion, Spontaneous - etiology
Adult
Arthritis, Rheumatoid - complications
Denmark - epidemiology
Female
Humans
Pregnancy
Registries
Risk
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Zusammenfassung:Abstract Objectives To investigate the influence of RA or preclinical RA on the risk of spontaneous abortion (SA) while taking age and duration of RA into consideration. Methods By linkage of data from Danish national registries, we established a nationwide cohort of pregnancies in Denmark from 1 January 1977 to 31 December 2014. We used multiple logistic regression to estimate; odds ratios (OR) for SA in women with RA or preclinical RA, compared with women without, and OR for SA by maternal age in women with RA or preclinical RA. Results A total of 2 612 529 pregnancies were included. Women aged
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/kez565