Increase in Streptococcus pneumoniae serotype 3 associated parapneumonic pleural effusion/empyema after the introduction of PCV13 in Germany

Pediatric pneumococcal pneumonia complicated by parapneumonic pleural effusion/empyema (PPE/PE) remains a major concern despite general immunization with pneumococcal conjugate vaccines (PCVs). In a nationwide pediatric hospital surveillance study in Germany we identified 584 children

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Veröffentlicht in:Vaccine 2020-01, Vol.38 (3), p.570-577
Hauptverfasser: Goettler, D., Streng, A., Kemmling, D., Schoen, C., von Kries, R., Rose, M.A., van der Linden, M., Liese, J.G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Pediatric pneumococcal pneumonia complicated by parapneumonic pleural effusion/empyema (PPE/PE) remains a major concern despite general immunization with pneumococcal conjugate vaccines (PCVs). In a nationwide pediatric hospital surveillance study in Germany we identified 584 children
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2019.10.056