Kidney function and cognitive impairment among older hospitalized patients: a comparison of four glomerular filtration rate equations

Background The relationship between the estimated glomerular filtration rate (eGFR) and cognitive impairment may change as a function of the equation used. We aimed at investigating the association between four different eGFR equations and cognitive impairment among older hospitalized patients. Meth...

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Veröffentlicht in:Aging clinical and experimental research 2020-05, Vol.32 (5), p.841-850
Hauptverfasser: Pierpaoli, Elisa, Fabi, Katia, Lenci, Federica Francesca, Ricci, Maddalena, Di Rosa, Mirko, Onder, Graziano, Volpato, Stefano, Ruggiero, Carmelinda, Cherubini, Antonio, Corsonello, Andrea, Lattanzio, Fabrizia
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Sprache:eng
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Zusammenfassung:Background The relationship between the estimated glomerular filtration rate (eGFR) and cognitive impairment may change as a function of the equation used. We aimed at investigating the association between four different eGFR equations and cognitive impairment among older hospitalized patients. Methods Our series consisted of 795 older patients consecutively admitted to 7 geriatric and internal medicine acute care wards. The eGFR was calculated by Chronic Kidney Disease Epidemiologic Collaboration (CKD-EPI), Cockcroft-Gault (CG), Berlin Initiative Study (BIS) and Full Age Spectrum (FAS) equations. Study outcomes were total Mini Mental State Examination (MMSE) 
ISSN:1720-8319
1594-0667
1720-8319
DOI:10.1007/s40520-019-01405-1