Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Objective The obesity/overweight may have an influence on APL outcomes. Methods This is the biggest multicentre analysis on 1320 APL patients treated with AIDA‐induction and risk‐adapted consolidation between 1996 and 2012. Patients body mass index (BMI) was classified as underweight (

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Veröffentlicht in:European journal of haematology 2020-03, Vol.104 (3), p.162-169
Hauptverfasser: Sobas, Marta, Rodriguez‐Veiga, Rebeca, Vellenga, Edo, Paluszewska, Monika, De la Serna, Javier, García‐Álvarez, Flor, Gil, Cristina, Brunet, Salut, Bergua, Juan, González‐Campos, Jose, Ribera, José María, Tormo, Mar, González, Marcos, Fernández, Isolda, Benavente, Celina, González‐Sanmiguel, Jose D., Esteve, Jordi, Pérez‐Encinas, Manuel, Salamero, Olga, Manso, Felix, Lowenberg, Bob, Sanz, Miguel A., Montesinos, Pau
Format: Artikel
Sprache:eng
Schlagworte:
acute promyelocytic leukemia
Acute promyeloid leukemia
AIDA protocol
Body mass index
Body weight
Chemotherapy
Multivariate analysis
Obesity
outcome
Overweight
Promyeloid leukemia
Risk factors
Underweight
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Zusammenfassung:Objective The obesity/overweight may have an influence on APL outcomes. Methods This is the biggest multicentre analysis on 1320 APL patients treated with AIDA‐induction and risk‐adapted consolidation between 1996 and 2012. Patients body mass index (BMI) was classified as underweight (
ISSN:0902-4441
1600-0609
DOI:10.1111/ejh.13346