CD10 expression identifies a subset of human perivascular progenitor cells with high proliferation and calcification potentials

The tunica adventitia ensheathes arteries and veins and contains presumptive mesenchymal stem cells (MSCs) involved in vascular remodeling. We show here that a subset of human adventitial cells express the CD10/CALLA cell surface metalloprotease. Both CD10+ and CD10− adventitial cells displayed phen...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2020-02, Vol.38 (2), p.261-275
Hauptverfasser:	Ding, Lijun, Vezzani, Bianca, Khan, Nusrat, Su, Jing, Xu, Lu, Yan, Guijun, Liu, Yong, Li, Ruotian, Gaur, Anushri, Diao, Zhenyu, Hu, Yali, Yang, Zhongzhou, Hardy, W. Reef, James, Aaron W., Sun, Haixiang, Péault, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult adventitia Aged Aged, 80 and over Arteries Biomedical materials Calcification Calcification (ectopic) Calcification, Physiologic - genetics CD10 Cell culture Cell cycle Cell fate Cell Proliferation Cell surface Cycle protein Gene expression GLI1 Humans mesenchymal stem cell Mesenchyme Metalloproteinase Middle Aged Neprilysin - metabolism osteogenesis Progenitor cells SHH Signaling Stem cells Stem Cells - metabolism vascular calcification
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