Intuitive neuromyoelectric control of a dexterous bionic arm using a modified Kalman filter

•Neural and electromyographic signals can be used together to improve estimates of motor intent.•Ad-hoc thresholds and gains improve prosthetic control by reducing unintended movement.•Thresholds and gains can be optimized offline and translate to functional improvements online.•Computational efficiency of the modified Kalman filter enables training and real-time use of a portable prosthetic control system in a home environment.•Participants successfully performed various activities of daily living in lab and at home. Multi-articulate prostheses are capable of performing dexterous hand movements. However, clinically available control strategies fail to provide users with intuitive, independent and proportional control over multiple degrees of freedom (DOFs) in real-time. We detail the use of a modified Kalman filter (MKF) to provide intuitive, independent and proportional control over six-DOF prostheses such as the DEKA “LUKE” arm. Input features include neural firing rates recorded from Utah Slanted Electrode Arrays and mean absolute value of intramuscular electromyographic (EMG) recordings. Ad-hoc modifications include thresholds and non-unity gains on the output of a Kalman filter. We demonstrate that both neural and EMG data can be combined effectively. We also highlight that modifications can be optimized to significantly improve performance relative to an unmodified Kalman filter. Thresholds significantly reduced unintended movement and promoted more independent control of the different DOFs. Gains were significantly greater than one and served to ease movement initiation. Optimal modifications can be determined quickly offline and translate to functional improvements online. Using a portable take-home system, participants performed various activities of daily living. In contrast to pattern recognition, the MKF allows users to continuously modulate their force output, which is critical for fine dexterity. The MKF is also computationally efficient and can be trained in less than five minutes. The MKF can be used to explore the functional and psychological benefits associated with long-term, at-home control of dexterous prosthetic hands.