High-field NMR with dissolution triplet-DNP

[Display omitted] •Development of an instrument for high-field NMR with dissolution DNP using triplet electrons.•Triplet-DNP can transfer highly polarized samples in the solid state at room temperature.•220-fold enhancement of 13C liquid-state NMR signals at 11.7 T. Dissolution dynamic nuclear polarization (DNP) has wide variety of important applications such as real-time monitoring of chemical reactions and metabolic imaging. We construct DNP using photoexcited triplet electron spins (Triplet-DNP) apparatus combined with dissolution apparatus for solution NMR in a high magnetic field. Triplet-DNP enables us to obtain high nuclear polarization at room temperature. Solid-state samples polarized by Triplet-DNP are transferred to a superconducting magnet and dissolved by injecting aqueous solvents. The 13C polarization of 0.22% has been obtained for [caryboxy-13C]benzoic acid-d in the liquid state. Our results show that Triplet-DNP can be applied to real-time monitoring with solution NMR.